个人简历:
陈林,
长期从事磁共振成像及图像重建算法研究,推动磁共振新技术在临床中的运用。迄今,共发表 SCI 收录论文 40 多篇,其中以第一或通信作者在《Nature Communications》、《Medical Image Analysis》、《NeuroImage》、《Magnetic Resonance in Medicine》等期刊上发表 17 篇;研究成果获福建省自然科学优秀学术论文一等奖、国际华人医学磁共振学会青年研究学者一等奖、国际医学磁共振年会 (ISMRM) Summa Cum Laude Merit Award、磁共振领域顶级期刊《Magnetic Resonance in Medicine》和《Journal of Magnetic Resonance》编辑推荐和杂志封面;入选博鱼体育登录南强青年拔尖人才、厦门市高层次留学人才、福建省高层次人才;主持国家自然科学基金、深圳市基础研究重点项目、福建省自然科学基金等多个科研项目。
学历:
2011年 博鱼体育登录工学学士,电子信息科学与技术专业
2014年 博鱼体育登录工程硕士,电子与通信工程专业
2015-2017年 美国约翰霍普金斯大学,联合培养博士生
2017年 博鱼体育登录工学博士, 电磁场与微波技术专业
2018-2020年 美国约翰霍普金斯大学,博士后
2021.01至今 博鱼体育登录电子科学系,副教授
研究方向:
磁共振成像、分子影像、医学影像处理与分析、机器学习与人工智能
主讲课程:
信号与系统
信号与系统实验
磁共振成像实验
学术兼职:
International Society for Magnetic Resonance in Medicine, ISMRM国际医学磁共振学会会员。
Neuroimage, Magnetic Resonance in Medicine, Journal of Magnetic Resonance, Frontiers in Neuroscience,NMR in biomedicine等国际主流期刊审稿人。
成果奖励:
2021,福建省高层次人才
2021,厦门市高层次留学人才
2020,国际华人医学磁共振学会青年研究学者一等奖
2019,国际医学磁共振学会(ISMRM)口头报告金奖
2019,国际华人医学磁共振学会青年研究学者三等奖
2018,福建省第十三届自然科学优秀学术论文一等奖
课题项目:
[1] 高灵敏脑葡萄糖代谢成像早期诊断阿尔茨海默病的方法研究,国家自然科学基金,2024.1-2026.12,主持
[2] 基20220281重大疾病创新诊断标志物研究,深圳市基础研究重点项目,2023.2-2026.2,子课题负责人
[3] 新型脑葡萄糖摄取磁共振成像方法研究,福建省自然科学基金,2022.8-2025.8,主持
近五年代表作:(一作或通信)
1. Chen L, Schar M, Chan KWY, Huang J, Wei Z, Lu H, Qin Q, Weiss RG, van Zijl PCM, Xu J. In vivo imaging of phosphocreatine with artificial neural networks. Nature Communications 11, 1072 (2020).
2. Zhou Y, van Zijl PCM, Xu X, Xu J, Li Y, Chen L, Yadav NN. Magnetic resonance imaging of glycogen using its magnetic coupling with water. Proceedings of the National Academy of Sciences of the United States of America 117, 3144-3149 (2020).
3. Huang J, van Zijl PCM, Han X, Dong CM, Cheng GWY, Tse KH, Knutsson L, Chen L, Lai JHC, Wu EX, Xu J, Chan KWY. Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI. Science Advances 6, eaba3884 (2020).
4. Chen X, Wu J, Yang Y, Chen H, Zhou Y, Lin L, Wei Z, Xu J, Chen Z, Chen L*. Boosting quantification accuracy of chemical exchange saturation transfer MRI with a spatial-spectral redundancy-based denoising method. NMR in Biomedicine 37, e5027 (2024).
5. Chen H, Chen X, Lin L, Cai S, Cai C, Chen Z, Xu J, Chen L*. Learned spatiotemporal correlation priors for CEST image denoising using incorporated global-spectral convolution neural network. Magnetic Resonance in Medicine 90, 2071-2088 (2023).
6. Chen X, Wang W, Huang J, Wu J, Chen L*, Cai C, Cai S, Chen Z. Ultrafast water-fat separation using deep learning-based single-shot MRI. Magnetic Resonance in Medicine 87, 2811-2825 (2022).
7. Chen L, Wei Z, Chan KW, Li Y, Suchal K, Bi S, Huang J, Xu X, Wong PC, Lu H, van Zijl PC, Li T, Xu J. D-Glucose uptake and clearance in the tauopathy Alzheimer's disease mouse brain detected by on-resonance variable delay multiple pulse MRI. Journal of Cerebral Blood Flow & Metabolism 41, 1013-1025 (2021).
8. Chen L, van Zijl PCM, Wei Z, Lu H, Duan W, Wong PC, Li T, Xu J. Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging. Neuroimage 236, 118071 (2021).
9. Chen L, Liu J, Chu C, Han Z, Yadav N, Xu J, Bai R, Staedtke V, Pearl M, Walczak P, van Zijl P, Janowski M, Liu G. Deuterium oxide as a contrast medium for real-time MRI-guided endovascular neurointervention. Theranostics 11, 6240-6250 (2021).
10. Chen L*, Cao S, Koehler RC, van Zijl PCM, Xu J. High-sensitivity CEST mapping using a spatiotemporal correlation-enhanced method. Magnetic Resonance in Medicine 84, 3342-3350 (2020).
11. Chen L, Wei Z, Chan KWY, Cai S, Liu G, Lu H, Wong PC, van Zijl PCM, Li T, Xu J. Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI. Neuroimage 188, 380-390 (2019).
12. Chen L, Wei Z, Cai S, Li Y, Liu G, Lu H, Weiss RG, van Zijl PCM, Xu J. High-resolution creatine mapping of mouse brain at 11.7 T using non-steady-state chemical exchange saturation transfer. NMR in Biomedicine 32, e4168 (2019).
13. Chen L, Barker PB, Weiss RG, van Zijl PCM, Xu J. Creatine and phosphocreatine mapping of mouse skeletal muscle by a polynomial and Lorentzian line-shape fitting CEST method. Magnetic Resonance in Medicine 81, 69-78 (2019).